Works by discipline "orvostudományok > gyógyszerészeti tudományok"

A

Ahmed Aimun Abdelgaffar Elhassan
Pharmacological investigations of natural β2-adrenoceptors agonists on rat uterus in vitro and in silico studies.
PhD, University of Szeged.
(2012)

Almeida R.P. David
Rational molecular fragmentation model As a method for the structural analysis of large drugs: a case study concerning the conformations of carvedilol in terms of quantum theoretical and experimental NMR spectroscopy.
PhD, University of Szeged.
(2004)

Ambrus Rita
Improvement of the solubility and dissolution rate of nifluminic acid to achieve rapid drug release.
PhD, University of Szeged.
(2007)

Amir Bashiri-Shahroodi
Dropping method as a new possibility in preparation of solid dispersions.
PhD, University of Szeged.
(2008)

B

Bajdik János
Effects of film coating on processibility of dymenhydrinate crystals.
PhD, University of Szeged.
(2003)

Baki Gabriella
Formulation and Investigation of Eroding Hydrophilic Matrix Systems.
PhD, University of Szeged.
(2011)

Bakonyi Mónika
Improved skin penetration using active and passive enhancement methods.
PhD, University of Szeged.
(2018)

Balázs Boglárka
Investigation of the skin barrier function and transdermal drug delivery techniques.
PhD, University of Szeged.
(2016)

Balázs Árpád
Structural diversity-driven synthesis of cycloalkane-based heterocycles and 1,3-bifunctional compounds.
PhD, University of Szeged.
(2010)

Barta Petra
Synthesis and conformational analysis of novel naphthoxazine-fused polyheterocycles.
PhD, University of Szeged.
(2018)

Bartos Csilla
Application of wet milling techniques to produce micronized and nanonized drug pre-dispersions for the development of intranasal formulations.
PhD, University of Szeged.
(2016)

Bartus Éva
Bottom-up design of foldamers for protein surface recognition.
PhD, University of Szeged.

Benedek Gabriella
Syntheses and stereochemistry of hydroxy-substituted alicyclic β-amino acid derivatives.
PhD, University of Szeged.
(2010)

Benkő Ria
Analysis of hungarian hospital antibacterial use from different aspects.
PhD, University of Szeged.
(2009)

Berkó Szilvia
Formulation of rectal suppositories containing diuretic drugs and their biopharmaceutical studies.
PhD, University of Szeged.
(2002)

Berényi Ágnes
Anticancer effects of estrone derivatives and nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 inhibitors.
PhD, University of Szeged.
(2013)

Bocsik Alexandra
Modulation of tight junctions by peptides to increase drug penetration across biological barriers.
PhD, University of Szeged.
(2016)

Bor Andrea
Geriatric falls and risk factors.
PhD, University of Szeged.
(2017)

Dr. Borcsa Botond Lajos
Investigations of diterpene alkaloids isolated from Aconitum anthora L. and A. moldavicum L., and of aconitine-derived lipo-alkaloids.
PhD, University of Szeged.
(2014)

Dr. Buchholcz Gyula
Development and characterization of modified release oral preparations containing riboflavin.
PhD, University of Szeged.
(2015)

Budai-Szűcs Mária
Formulation and Investigation of Gel-Emulsions Containing Polymeric Emulsifiers.
PhD, University of Szeged.
(2008)

Dr. Bálint Erika
Khat (Catha edulis) a contoversial plant: blessing or curse?
PhD, University of Szeged.
(2013)

Bóta Judit
The effects of female sexual hormones on α1- and α2- adrenergic receptor subtypes in the pregnant rat myometrium.
PhD, University of Szeged.
(2017)

Bózsity Noémi
Antiproliferative and antimetastatic properties of D-ring modified estrogen analogs on cervical cancer cell lines.
PhD, University of Szeged.
(2018)

Bölcskei Éva
Optimization of process parameters of coated pellet production.
PhD, University of Szeged.
(2012)

C

Cherepanova Maria
A stereocontrolled access to functionalized cispentacins and acyclic β2,3-amino acids through oxidative ring cleavage.
PhD, University of Szeged.
(2014)

Chvatal Anita
Formulation and aerodynamic evaluation of carrier-free dry powder inhalation systems containing meloxicam.
PhD, University of Szeged.
(2019)

Csillag Kinga
Stereoselective synthesis of monoterpene-based 1,3-diamines and 3-amino-1,2-diols and their application in enantioselective transformations.
PhD, University of Szeged.
(2014)

Dr. Csizmazia Eszter
Drug permeation study through biological membrane barriers.
PhD, University of Szeged.
(2011)

Csonka Dénes
Investigation of pregnancy induced adrenergic denervation in the rat.
PhD, University of Szeged.
(2010)

Csupor Dezső
Investigation of the diterpene alkaloids of Aconitum species native to the Carpathian Basin.
PhD, University of Szeged.
(2007)

Csupor-Löffler Boglárka
Activity-guided investigation of antiproliferative secondary metabolites of Asteraceae species.
PhD, University of Szeged.
(2012)

Csábi József
Preparation of novel bioactive semi-synthetic ecdysteroid derivatives.
PhD, University of Szeged.
(2017)

Csányi Adrienn
The role of the aquaporin 5 in the function of late pregnant rat uterus: pharmacological studies.
Régi típusú doktori értekezés, University of Szeged.

Csányi Erzsébet
Quality Development of Semisolid Dermal Drug Delivery Systems.
PhD, University of Szeged.
(2004)

D

Dr. Deák Beáta
Investigation of the effects of nociceptin and nocistatin on pregnant uterine contractions in vitro.
PhD, University of Szeged.
(2013)

Dobi Krisztina
Selection and testing of protein target focused compound libraries using chemoinformatics methods integrated with MTS biological assay.
PhD, University of Szeged.
(2017)

Domokos Dóra
Investigation of the RhoA and Rho-kinases in the rat myometrium and cervix.
PhD, University of Szeged.

Doró Péter
Utilization of oral antidiabetic drugs in Csongrád county between 1998 and 2004: : adherence and persistence with therapy.
PhD, University of Szeged.
(2007)

Ducza Eszter
The role of alfa1-adrenergic receptor subtypes in myometral contraction in rat.
PhD, University of Szeged.
(2002)

E

Evanics Ferenc
Structure Elucidation of Natural Diterpenes by NMR Spectroscopy.
PhD, University of Szeged.
(2005)

F

Fehér András
Formulation and investigation of in situ gelling lyotropic liquid crystalline systems.
PhD, University of Szeged.
(2006)

Fekete Beáta
Syntheses and transformations of alicyclic β-aminohydroxamic acids.
PhD, University of Szeged.

Ferenc Györgyi
Regioselective synthesis and MS/MS study of alkyl (guanin-9-yl) acetates. Synthesis of of peptide nucleic acid oligomers.
PhD, University of Szeged.
(2005)

Fitz Mónika
Enzymatic kinetic resolution of β-amino acid derivatives.
PhD, University of Szeged.
(2009)

G

dr Galla Zsolt
Preparation of pharmaceutically important enantiomer components through lipase catalysed acylation and hydrolysis.
PhD, University of Szeged.
(2017)

Gedey Szilvia
Application of ß-amino acids in lipase-catalysed kinetic resolutions and in combinatorial syntheses.
PhD, University of Szeged.
(2005)

George Zapantis
In vitro and in vivo evaluation of semisolid dosage forms for transdermal application of Ketamine.
PhD, University of Szeged.
(2008)

Gombás Ágota
The study of physico-chemical properties of crystalline and amorphous materials.
PhD, University of Szeged.
(2008)

Gonda Tímea
Stereoselective synthesis and application of bi- and trifunctional monoterpene-based compounds.
PhD, University of Szeged.
(2018)

Gottnek Mihály
Design and characterization of mucoadhesive hydroxypropyl cellulose oral films.
PhD, University of Szeged.
(2017)

Gyarmati Zsuzsanna
Synthesis, enzymatic resolution and transformations of alicyclic cis- and trans-1,2-difunctional compounds.
PhD, University of Szeged.
(2004)

Gyovai András
Characterization of antineoplastic properties of novel androstane-based synthetic steroids.
PhD, University of Szeged.

Gyulai Orsolya
Development of directly compressible ambroxol hydrochloride spherical crystals.
PhD, University of Szeged.
(2018)

Gyónfalvi Szilvia
Syntheses and applications of novel beta-amino acids.
PhD, University of Szeged.
(2009)

Gál Adrienn
Different roles of the alpha2-adrenoceptor subtypes in the uterine function in vitro in the rat.
PhD, University of Szeged.
(2010)

Gálik Márta
An investigation of the effects of beta(2)-mimetics, gestagens and an alpha(2)-antagonist in premature labour model in the rat.
PhD, University of Szeged.
(2008)

Göcző Hajnalka
Spherical crystallization of drug materials for direct tagletmaking.
PhD, University of Szeged.
(2002)

H

Hackler László
Development of chemically modified glass surfaces and methods for microarray technologies.
PhD, University of Szeged.
(2004)

Hajagos-Tóth Judit
Modification of the myometrial relaxing effect of nifedipine in vitro and in vivo.
PhD, University of Szeged.
(2011)

Hajdu Zsanett
An ethnopharmacological survey conducted in the Bolivian Amazon, and identification of N-alkylamides and lignans from Lepidium meyenii and Heliopsis helianthoides var. scabra with effects on the central nervous system.
PhD, University of Szeged.
(2014)

Hajnal Ágnes
Involvement of nitric oxide and reactive oxygen species in the early and delayed antiarrhythmic effects of preconditioning.
PhD, University of Szeged.
(2015)

Hassan M. Abdo Hassan Bin
Increasing the bioavailability of gemfibrozil via complex formation with cyclodextrins and study of the complexes characteristics.
PhD, University of Szeged.
(2006)

Hegedűs Ágota
Comparison of the effect of granulation and drying techniques on the quality of a pharmaceutical product with a high active ingredient content.
PhD, University of Szeged.
(2008)

Hegyesi Diána
Study of the widely used ethylcellulose polymer as film forming and matrix former agent.
PhD, University of Szeged.
(2016)

Hetényi Anasztázia
Investigation of dynamic processes and self-organization by spectroscopic methods and molecular modelleng.
PhD, University of Szeged.
(2005)

Horvát Gabriella
Mucoadhesive polymers in ophthalmic therapy.
PhD, University of Szeged.
(2016)

Horvát Sándor
Targeting pharmacons to the brain via the nasal pathway.
PhD, University of Szeged.
(2009)

Hunyadi Attila
Serratula wolffii, as a promising source of ecdysteroids.
PhD, University of Szeged.
(2006)

Dr. Háznagy-Radnai Erzsébet
Examination of the volatile and non-volatile components of Hungarian Stachys species.
PhD, University of Szeged.
(2007)

dr. Hódi Ágnes
Antioxidants may reduce the smooth muscle-relaxing action of β2-adrenergic receptor agonists.
PhD, University of Szeged.
(2016)

Hőgyes Endre
Effects of polyunsaturated fatty acids on brain development and aging.
PhD, University of Szeged.
(2004)

I

I. Hamedelniel Elnazeer
Development and characterization of matrix pellets prepared by extrusion / sheronization of atenolol.
PhD, University of Szeged.
(2011)

J

Juhász Márta
Mass Spectrometric Behaviour of Phosphorus-containing Heterocycles and Ring-chain Tautomerism of some 1,3-O,N-heterocycles.
PhD, University of Szeged.
(2008)

Jójárt Balázs
Quantitative structure-activity relationship calculations in the field of oxytocin receptor antagonists.
PhD, University of Szeged.
(2006)

Jójárt Imre
The importance of magnesium stearate in pharmaceutical industry and in the preformulation studies of medicated chewing gums.
PhD, University of Szeged.
(2014)

Jójártné Laczkovich Orsolya
Amorphization of a crystalline active agent with the aim of pharmaceutical technological formulation.
PhD, University of Szeged.
(2012)

K

dr Kalmár Éva
Challenges of HPLC method development and validation for the assay of combined drug products.
PhD, University of Szeged.
(2014)

Kardos Márton
Syntheses of functionalised β-amino acids through ring-opening/cross metathesis.
PhD, University of Szeged.
(2018)

Karimi Keyhaneh
Development of dry powder inhalation systems using ciprofloxacin hydrochloride: new aspects of formulation by means of quality by design approach.
PhD, University of Szeged.
(2019)

Dr. Katona Gábor
Formulation of microcomposites and pastilles using spray-drying and melt technology.
PhD, University of Szeged.
(2017)

Kelemen András
Dynamic Force Measurements in Preformulation of Solid Dosage Forms.
PhD, University of Szeged.
(2012)

Kelen Ákos
A mikrohullámú energia alkalmazása az ún. egyterű örvényáramú granuláló és vakuumszárító berendezésekben; Új orális, kombinált hatóanyag-tartalmú tabletta kifejlesztése, különös tekintettel, annak dielektromos vakuumszárítására.
PhD, University of Szeged.
(2006)

Kis Kornélia
The role of TLR2 and TLR4 in the immune functions of epidermal cells and in the pathogenesis of acne.
PhD, University of Szeged.
(2006)

Kiss Lóránd
Effects of absorption enhancer surfactants on culture models of intestinal and vascular barriers.
PhD, University of Szeged.
(2014)

Kiss Tivadar
Phytochemical, pharmacological and toxicological studies of alkaloid- and sesquiterpene lactone-containing medicinal plants.
PhD, University of Szeged.
(2017)

Kolarovszki-Sipiczki Zoltán
Role of the adrenergic system in regulation of the resistance of the cervix of pregnant rat.
PhD, University of Szeged.
(2007)

Korbely Anita
Preparation and investigation of polymethacrylate-based matrix systems.
PhD, University of Szeged.
(2013)

Korteby Yasmine
Study of fluid bed granulation processes with new technology approaches.
PhD, University of Szeged.
(2018)

Kovács Anita
Structural evaluation of w/o/w multiple emulsions.
PhD, University of Szeged.
(2008)

Kovács Bernadett
From cyclic peptides to terphenyl quinones: biologically active metabolites from Hungarian mushrooms.
PhD, University of Szeged.
(2019)

Kovács Adriána
Isolation and structure elucidation of compounds with antitumor activity from Tamus communis and Xanthium italicum.
PhD, University of Szeged.
(2009)

Kristó Katalin
Investigation of proteins during processing into solid dosage forms.
PhD, University of Szeged.
(2010)

Kónya Magdolna
Study of the microstructure of creams prepared with different surfactants.
PhD, University of Szeged.
(2004)

Dr. Kürti Levente
Innovative pharmaceutical formulations and excipients for nasal delivery of drugs to target the systemic circulation.
PhD, University of Szeged.
(2012)

L

Lajter Ildikó
Biologically active secondary metabolites from Asteraceae and Polygonaceae species.
PhD, University of Szeged.
(2016)

Le Minh Tam
Stereoselective syntheses and application of limonene- and isopulegol-based bi- and trifunctional chiral ligands.
PhD, University of Szeged.

Ledneczki István
Szupersavakkal katalizált szerves szintézisek.
PhD, University of Szeged.
(2005)

Liktor-Busa Erika
Analysis of the ecdysteroid profile of Serratula wolffii roots.
PhD, University of Szeged.
(2008)

Láng Péter
Polymorph screening of a former drug candidate.
PhD, University of Szeged.
(2016)

M

Makai Melinda
Structure and drug release study of lamellar liquid crystals containing Brij 96 as nonionic surfactant.
PhD, University of Szeged.
(2006)

Maroda Mónika
Preparation and investigation of cross-linked hyaluronic acid nanoparticle systems.
PhD, University of Szeged.
(2013)

Matuz Mária
Quantitative and qualitative analysis of the hungarian ambulatory antibiotic consumption on national and regional level based on different data sources 1996-2007.
PhD, University of Szeged.
(2010)

Megyesi Rita
Kinetic and dynamic kinetic enzymatic resolutions of tetrahydro-ß-carboline and tetrahydroisoquinoline derivatives.
PhD, University of Szeged.

Miklós Ferenc
Application of gamma-oxocarboxylic acids and amino acid derivatives for the preparation of heterocycles; retro Diels-Alder reactions.
PhD, University of Szeged.
(2005)

Minorics Renáta
Ontogeny and functions of the estrogen receptor subtypes in the pregnant rat uterus; the influence of stereoisomerism on ligand-receptor interactions.
PhD, University of Szeged.
(2005)

Molnár Judit
Characterization of antiproliferative activities of triazolyl-steroid derivatives.
PhD, University of Szeged.
(2015)

Mándity Istvan
Tailoring β-peptide foldamers by backbone stereochemistry and side-chain topology.
PhD, University of Szeged.
(2011)

dr. Mártha Csaba
Crystallinity changes of organic materials in pharmaceutical technology.
PhD, University of Szeged.
(2015)

N

Nekkaa Imane
The pharmaceutical chemical tendency towards continuous-flow processing: novel chemical reactivities and entities.
PhD, University of Szeged.

Nikowitz Krisztina
Manufacturing and investigation of coated pellets containing water-soluble active ingredients.
PhD, University of Szeged.
(2014)

O

Olajos Gábor
Beta-amino acid substitutions in beta-sandwich model proteins.
PhD, University of Szeged.

dr. Orbán-Gyapai Orsolya
Pharmacological screening of Polygonaceae species and isolation of biologically active compounds from Rumex aquaticus L. and Rumex thyrsiflorus Fingerh.
PhD, University of Szeged.
(2017)

P

Palkó Márta
Syntheses and transformations of alicyclic ß-amino acid derivatives.
PhD, University of Szeged.
(2005)

Pallagi Edina
New possibilities for the development of iron(II) sulfate containing solid products with sustained drug release.
PhD, University of Szeged.
(2005)

Dr. Petró Éva
Regulatory evaluation of drug release from dermal semisolid dosage forms.
PhD, University of Szeged.
(2014)

Pomázi Anita
Development of co-spray-dried carrier-based microcomposites for local pulmonary application of meloxicam.
PhD, University of Szeged.
(2014)

Pongrácz Zita
Ecdysteroids isolated from Silene Italica ssp. nemoralis.
PhD, University of Szeged.
(2003)

Pál Ákos
Investigation of interactions between ABC transporters and their lipid environment - Effect of membrane cholesterol content on the function of human ABCG2(BCRP/MXR).
PhD, University of Szeged.
(2008)

Páldy Eszter
One step closer to the role of the brain CB2 cannabinoid receptors: interaction with the μ-opioid system.
PhD, University of Szeged.
(2008)

Pénzes Tímea
Optimization and evaluation of topical used pharmaceutical organogels.
PhD, University of Szeged.
(2005)

R

Rajnai Zsuzsanna
Characterization of toxicologically significant efflux transporters and their interactions with drugs.
PhD, University of Szeged.
(2018)

Reisi Nassab Parya
Enhancement of the dissolution of meloxicam in binary systems.
PhD, University of Szeged.
(2007)

Remete Attila Márió
Application of nucleophilic fluorinating reagents for the synthesis and transformations of cyclic β-amino acid derivatives.
PhD, University of Szeged.

Roza Orsolya
Promising assets of South Africa? Cyclopia genistoides and Hoodia gordonii.
PhD, University of Szeged.
(2016)

Rédei Dóra
Isolation and Structural Characterization of New Jatrophane Diterpene Polyesters from Euphorbia Serrulata and Euphorbia Mongolica.
PhD, University of Szeged.
(2005)

Réthy Borbála
Antitumour effect of plant extracts and their constituents on cancer cell lines.
PhD, University of Szeged.
(2008)

S

dr. Sas Judit
Selective N-alkylation/α-arylation of N-heterocycles.
PhD, University of Szeged.
(2016)

Schuster Ildikó
Syntheses and transformations of difunctional tetrahydroisoquinolines.
PhD, University of Szeged.
(2010)

Schönstein László
Enzymatic resolution of tetrahydroisoquinoline derivatives in batch and continuous-flow systems.
PhD, University of Szeged.
(2014)

Seres Adrienn
Sexual hormone effects of honeybee (Apis mellifera) drone milk in male and female rats.
PhD, University of Szeged.
(2014)

Sipos Barbara
Investigation of physicochemical characteristics and tablettability of titanate nanotube-active drug composites.
PhD, University of Szeged.

Sipos László
High-performance liquid chromatographic enantioseparation of unnatural β-amino acids on chiral stationary phases.
PhD, University of Szeged.
(2013)

Sipos Péter
Formulation optimization of ammonio methacrylate copolymer based sustained release microspheres.
PhD, University of Szeged.
(2008)

Solymár Magdolna
Enzymatic kinetic resolution of ß-amino and ß-hydroxy acid derivatives.
PhD, University of Szeged.
(2005)

Sovány Tamás
Modelling of the postcompressional properties of direct-compressed scored tablets with the use of artificial neural networks.
PhD, University of Szeged.
(2010)

Spiegl Gábor
The effects of experimental diabetes mellitus on the adrenergic functions of the rat uterus.
PhD, University of Szeged.
(2011)

dr. Sulyok Edvárd
Isolation and Structure Elucidation of Diterpenes from Euphorbia pannonica, E. esula and E. falcata.
PhD, University of Szeged.
(2013)

Szabados-Nacsa Ágnes
Improvement of the solubility and bioavailability of loratadine by pharmaceutical technological mtehods.
PhD, University of Szeged.
(2012)

Szalay Annamária
A few aspects on the importance of particle size enabling proper tabletting.
PhD, University of Szeged.
(2015)

Szatmári István
Syntheses and Transformations of α-Aminobenzylnaphthol Derivatives.
PhD, University of Szeged.
(2004)

Szolnoki Éva
β-Peptide foldamer helices with tailored diameters.
PhD, University of Szeged.
(2018)

Sztojkov-Ivanov Anita
High-performance liquid chromatographic separation of the enantiomers of amino compounds on chiral stationary phases.
PhD, University of Szeged.
(2009)

dr Szűcs Kálmán Ferenc
Development of smooth muscle electromyographic method: detection and interpretation of slow wave activities in gastrointestinal tract and pregnant uterus.
PhD, University of Szeged.
(2018)

Szűts Angéla
Study of the applicability of sucrose esters in hot-melt technology.
PhD, University of Szeged.
(2009)

Sütő Blanka
Development and investigation of nanostructured lipid carriers for transdermal drug delivery.
PhD, University of Szeged.
(2016)

T

Tari Tímea
Crystal habit optimization by means of impinging jet crystallization method.
PhD, University of Szeged.

Tasnádi Gábor
Direct enzymatic routes to β-substituted β-amino acid enantiomers.
PhD, University of Szeged.
(2010)

Tóth Barbara
Bioactive secondary metabolites from Juncaceae species.
PhD, University of Szeged.
(2017)

Tóth Diána
Synthesis and stereochemistry of new naphthoxazine derivatives.
PhD, University of Szeged.
(2010)

Tóth Noémi
Ecdysteroid profile of Silene viridiflora and the effect of 20-hydroxyecdysone on rat muscle fibres in vivo.
PhD, University of Szeged.
(2010)

Tóth Enikő
Comparative chemical analysis of Ballota species, with special respect to Ballota nigra, our new official plant in Ph. Hg. VIII.
PhD, University of Szeged.
(2009)

Tüske Zsófia
Influence of the surface free energy on the parameters of pellets.
PhD, University of Szeged.
(2006)

V

Vasas Andrea
Isolation and structure elucidation of diterpenes from Hungarian Euphorbia species.
PhD, University of Szeged.
(2006)

Venczel Márta
Pharmaceutical development of co-crystals.
PhD, University of Szeged.
(2012)

Dr. Veres Katalin
Variability and biologically active components of some Lamiaceae species.
PhD, University of Szeged.
(2007)

Verli Judit
Investigation of the coordinated interplay among β2-adrenergic receptors, phosphodiesterase 4 and the AKAP-PKA in the cAMP dependent relaxation of the late pregnant uterus.
PhD, University of Szeged.
(2013)

Viola Réka
Antidepressant consumption in hungary and health-related quality of life assessment in patients with depression.
PhD, University of Szeged.
(2008)

Ványolós Attila
Investigation of plants containing unusual ecdysteroids with ring in their side-chain.
PhD, University of Szeged.
(2012)

W

Winter Zoltán
Investigation of the transient receptor potential vanilloid 1 (TRPV1) ion channel.
PhD, University of Szeged.
(2013)

Z

Zalán Zita
Syntheses and ring-closures of difunctional tetrahydroisoquinolines.
PhD, University of Szeged.
(2006)

Á

dr. Ábrahámi Renáta
Stereocontrolled synthesis of functionalized fluorine-containing N-heterocycles through oxidative ring opening/ring closure with reductive amination.
PhD, University of Szeged.

Ö

Özge Gündüz
Biochemical, functional and pharmacological characterization of novel hexapeptide ligands targeting nociceptin/orphanin FQ receptor, in vitro and in vivo studies.
PhD, University of Szeged.
(2006)