Non-genomic actions of steroid hormones in pregnant and non-pregnant uterine tissues: in vivo and vitro studies

Mirdamadi Seyedmohsen
Non-genomic actions of steroid hormones in pregnant and non-pregnant uterine tissues: in vivo and vitro studies.
Doctoral thesis (PhD), University of Szeged.
(2023)

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Abstract in foreign language

It is known that the results of the non-genomic action can be the same as or even different from the effects mediated through the genomic pathway. For example, in the cardiovascular system and diabetes mellitus, the outcome of both signaling pathways is the same 27–30, but in breast cancer cell lines, their actions can be the opposite 26. Since the prompt actions of steroids on uterine contractility are not fully explored yet, we aimed to investigate the fast, non-genomic action of sex steroids (E2, progesterone (P4), T) and corticosteroids (MC fludrocortisone (FLD) and GC (DEX)) on uterine contractions and signaling pathways both late (22-day) pregnant and non-pregnant rats in vitro and in vivo as well.

Item Type:	Thesis (Doctoral thesis (PhD))
Creators:	Mirdamadi Seyedmohsen
Supervisor(s):	Supervisor Position, academic title, institution MTMT author ID Gáspár Róbert habilitált egyetemi docens, Farmakológiai és Farmakoterápiai Intézet SZTE / SZAOK 10010954
Subjects:	03. Medical and health sciences > 03.01. Basic medicine > 03.01.06. Pharmacology and pharmacy
Divisions:	Doctoral School of Pharmaceutical Sciences
Discipline:	Medicine > Pharmacy
Language:	English
Date:	2023. January 20.
Item ID:	11519
MTMT identifier of the thesis:	34117827
doi:	https://doi.org/10.14232/phd.11519
Date Deposited:	2022. Nov. 01. 09:01
Last Modified:	2023. Aug. 29. 12:55
Depository no.:	B 7253
URI:	https://doktori.bibl.u-szeged.hu/id/eprint/11519
Defence/Citable status:	Defended.

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